NUT1 Rabbit Monoclonal Antibody(ARB864)
Datasheet
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6656
RMB Please choose
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Nuclear protein in testis (NUT1 or NUTM1) is a nuclear protein encoded by the NUTM1 gene on chromosome 15 and normally expressed in testicular tissues. NUT1 is an unstructured protein with few orthologs, and shuttles between the nucleus and cytoplasm. NUT cancer (formerly NUT Midline Carcinoma) occurs after a gene fusion event between NUTM1 and often a bromodomain (BRD) family gene in about 75% of cases. NUTM1 less commonly fuses with NSD3, MXD4, MGA, ZNF532, CIC, and other rare variants, which are all considered to be NUT cancers.
Overview
|
Target |
NUT1 |
|
Host Species |
rabbit monoclonal antibody |
|
Molecular Weight |
120 kDa |
|
Purity |
ProA affinity purified IgG |
|
Species Cross-reactivity |
Human |
|
Form |
Liquid |
|
Applications |
IHC-P |
|
Swissprot ID |
Q86Y26 |
|
Immunogen |
Synthetic peptide corresponding to NUT1 |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
|
Storage Conditions |
-25°C to -18°C |
|
Dilutions |
IHC-P: 1:100-1:200 |
|
Subcellular Location |
Nucleus |
|
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), RT for 30 min |
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:100 - 1:200 |
Data
Immunohistochemical staining of human testicular tissue sections using NUT1 Rabbit Monoclonal Antibody (ARB864).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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