p16 Mouse Monoclonal Antibody(ARM877)
CAT.NO. : ARM6667
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Background
The p16 (p16INK4A) protein is a cyclin-dependent kinase (CDK) inhibitor that plays an important regulatory role in the cell cycle. By controlling the transition between the G1 and S phases through regulation of retinoblastoma protein, p16 decelerates cellular differentiation and therefore acts as a tumor suppressor, making it the key marker in several human cancers including head and neck cancer, perianal lesions, melanomas, gliomas, lymphomas, and some types of leukemia. p16 is also clinically indicated in carcinomas of the esophagus, pancreas, lung, biliary tract, liver, colon, and urinary bladder.
Application
Application |
Dilution Ratio |
IHC |
1:50 - 1:200 |
Overview
Target |
p16 |
Purity |
ProG affinity purified IgG |
Species Cross-reactivity |
Human |
Form |
Liquid |
Applications |
IHC-P |
Swissprot ID |
P42771 |
Immunogen |
Recombinant protein of p16 |
Data

Immunohistochemical staining of human Cervical Carcinoma tissue sections using p16 Mouse Monoclonal Antibody (ARM877).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
