p21 Mouse Monoclonal Antibody(ARM542)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6832
RMB Please choose
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
p21, also known as p21^Cip1^ , p21^Waf1^, Cyclin-Dependent Kinase Inhibitor 1, or CDK-Interacting Protein 1, functions to regulate cell cycle progression at G1 by inhibiting the activity of Cyclin-CDK2 or -CDK4 complexes. This cyclin-dependent kinase inhibitor is expressed in all adult human tissues, and decreased expression of p21 is linked to poor prognosis in a number of carcinomas including gastric carcinoma, non-small cell lung carcinoma, and thyroid carcinoma. p21 is also associated with favourable prognosis in several tumours.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
18,119 Da |
|
Chromosome Location |
Chromosome: 6; NC_000006.11 (36644237..36655116). Location: 6p21.2 |
|
3D Structure |
ModBase 3D Structure for P38936 |
|
Isotype |
IgG2a |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human small intestine tissue using p21 Mouse Monoclonal Antibody (ARM542).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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