p504s/AMACR Rabbit Monoclonal Antibody(ARM885)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6675
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
p504s, also known as α-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in β-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:400 |
Overview
|
Molecular Weight |
382 (198) |
|
Chromosome Location |
Chromosome: 5; NC_000005.9 (33987091..34008220, complement). Location: 5p13 |
|
OMIM |
214950 |
|
3D Structure |
ModBase 3D Structure for Q9UHK6 |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
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Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
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Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human prostate cancer tissue using p504s/AMACR Rabbit Monoclonal Antibody (ARM885).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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