p57 kip2 Mouse Monoclonal Antibody(ARM545)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6835
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
p57Kip2, also known as p57, is a tumour suppressor protein that causes cell cycle arrest at G1 by binding to G1 cyclin-CDK complexes. The p57Kip2 gene is a potential tumour suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms' tumour, and Beckwith Wiedemann syndrome. Anti-p57Kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Clonality |
Monoclonal |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Form/Format |
Tris Buffer, pH7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
Data
Immunohistochemical staining of human placenta tissue using p57 kip2 Mouse Monoclonal Antibody (ARM545).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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