PAPP A ELISA Antibody Duo

产品描述: PAPP A is a metalloprotease that belongs to the metzincin superfamily of zinc peptidases. The insulin-like growth factor binding protein 4 (IGFBP-4), as well as IGFBP-5 have been found to be specific substrates for PAPP A in vitro. htPAPP A is a widely recognized biochemical marker of Down syndrome (DS) that is used in the first trimester of pregnancy. htPAPP A level in maternal serum increases with gestational age until term. In cases of DS pregnancy, htPAPP A concentration in the first trimester is markedly decreased. Therefore, htPAPP A is currently used as a biochemical marker of DS in the first trimester of pregnancy in combination with free b-subunit of chorionic gonadotropin (bhCG) and nuchal translucency. ARG30198 PAPP A ELISA Duos, includes a capture antibody, ARG10507 PAPP A Protein antibody [4G11] and a detection antibody, ARG10508 PAPP A Protein antibody [3C8], for the quantification of PAPP A expression level by ELISA.
靶点名称: PAPP A
別名: PAPP A ELISA antibody; PAPP A antibody

CAT.NO. : ARG30198

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Size:

1 pair

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Product Details

内含物

货号	内含物名称	宿主克隆性	反应	应用	包装
ARG10507	anti-PAPP A antibody [4G11]	Mouse mAb	Hu	ELISA, WB	500 μg
ARG10508	anti-PAPP A antibody [3C8]	Mouse mAb	Hu	ELISA, WB	500 μg

概述

产品描述	PAPP A is a metalloprotease that belongs to the metzincin superfamily of zinc peptidases. The insulin-like growth factor binding protein 4 (IGFBP-4), as well as IGFBP-5 have been found to be specific substrates for PAPP A in vitro. htPAPP A is a widely recognized biochemical marker of Down syndrome (DS) that is used in the first trimester of pregnancy. htPAPP A level in maternal serum increases with gestational age until term. In cases of DS pregnancy, htPAPP A concentration in the first trimester is markedly decreased. Therefore, htPAPP A is currently used as a biochemical marker of DS in the first trimester of pregnancy in combination with free b-subunit of chorionic gonadotropin (bhCG) and nuchal translucency. ARG30198 PAPP A ELISA Duos, includes a capture antibody, ARG10507 PAPP A Protein antibody [4G11] and a detection antibody, ARG10508 PAPP A Protein antibody [3C8], for the quantification of PAPP A expression level by ELISA.
靶点名称	PAPP A
別名	PAPP A ELISA antibody; PAPP A antibody

属性

存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名	ELISA Antibody Duo for PAPP A
研究领域	Cell Biology and Cellular Response antibody

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