PAX-2 Rabbit Monoclonal Antibody(ARB521)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6813
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
PAX-2 is a member of the PAX family of transcription factors that, together with PAX-8, is involved in the regulation of the organogenesis of the kidney and the Müllerian system.
Among the non-neoplastic tissue, PAX-2 was expressed in glomerular parietal epithelial cells, renal collecting duct cells, atrophic renal tubular cells, epithelial cells of ovarian surface, fallopian tube, endocervix, endometrium. Among the primary neoplasms, PAX-2 was mainly noted in renal cell carcinoma, carcinomas of Müllerian origin, nephrogenic adenomas.
Recent investigations have indicated that PAX-2 could serve as a useful immunohistochemical marker that can assist in the diagnosis of epithelial tumors of the kidney, as well as some gynecologic (Müllerian) neoplasms.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:200 |
Overview
|
Predicted Molecular Wt |
45kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
Q02966 |
|
Subcellular location |
Nucleus |
|
Recommended method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
|
Immunogen |
Synthetic peptide corresponding to PAX-2 residues within aa300-400 of PAX-2 was used as an immunogen |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human uterus tissue using PAX-2 Rabbit Monoclonal Antibody(ARB521)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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