Pax 7 Rabbit Monoclonal Antibody(ARA920)
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Rabbit
- Clonality:Monoclonal
- Target:Pax 7
-
Brand:
CAT.NO. : ARA6755
RMB Please choose
RMB Please choose
Product Details
Background
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:50-1:200 |
Overview
|
Antibody Type |
Recombinant Rabbit monoclonal Antibody |
|
Immunogen |
Synthetic peptide within Human PAX7 aa 381-430 / 505 |
|
Species Reactivity |
Human (Predicted: Mouse, Rat) |
|
Validated Applications |
WB, IHC-P |
|
Molecular Weight |
Predicted band size: 55 kDa |
|
Positive Control |
HeLa cell lysate, MCF7 cell lysate, human skin tissue |
|
Conjugation |
unconjugated |
|
Form |
Liquid |
|
Concentration |
1μg/μl |
|
Storage Buffer |
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG |
|
Purification Method |
Protein A affinity purified |
Data
Immunohistochemical staining of human skin tissue using Pax 7 Rabbit Monoclonal Antibody(ARA920)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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