Phospho FAK Antibody Panel
Key features and details
- 产品描述:
- 靶点名称:
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Product Details
| 货号 | 内含物名称 | 宿主克隆性 | 反应 | 应用 | 包装 |
|---|---|---|---|---|---|
| ARG51136 | anti-FAK antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB | 50 μl |
| ARG51706 | anti-FAK phospho (Tyr397) antibody | Rabbit pAb | Hu, Ms, Rat | IHC-P, WB | 50 μl |
| ARG51831 | anti-FAK phospho (Tyr576 / Tyr577) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, WB | 50 μl |
| ARG51624 | anti-FAK phospho (Tyr925) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, WB | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
| 产品描述 | Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival. Activation of FAK by integrin clustering leads to autophosphorylation at Tyr397, which is a binding site for the Src family kinases PI3K and PLCγ. Recruitment of Src family kinases results in the phosphorylation of Tyr407, Tyr576, and Tyr577 in the catalytic domain, and Tyr871 and Tyr925 in the carboxy-terminal region of FAK. Schaller, M.D. et al. (1994) Mol Cell Biol 14, 1680-8. Cobb, B.S. et al. (1994) Mol Cell Biol 14, 147-55. Parsons, J.T. et al. (2000) Oncogene 19, 5606-13. Schlaepfer, D.D. et al. (1994) Nature 372, 786-791. |
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| 靶点名称 | FAK |
| 別名 | Phospho FAK antibody; Phospho Focal adhesion kinase antibody; FAK antibody; FAK phospho (Tyr925) antibody; FAK phospho (Tyr397) antibody; FAK phospho (Tyr576 / Tyr577) antibody |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
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| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 全名 | Phospho Focal adhesion kinase (FAK) Antibody Panel |
|---|---|
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody |
ARG51136 anti-FAK antibody WB image
Western Blot: extracts from HeLa cells stained with anti-FAK antibody ARG51136 and the same antibody preincubated with blocking peptide.
ARG51624 anti-FAK phospho (Tyr925) antibody WB image
Western Blot: extracts from 293 cells stained with anti-FAK (phospho Tyr925) antibody ARG51624 (Lane 2) and the same antibody preincubated with blocking peptide (Lane1).
ARG51706 anti-FAK phospho (Tyr397) antibody WB image
Western Blot: extract from 293 cells untreated or treated with EGF stained with anti-FAK (phospho Tyr397) antibody ARG51706
ARG51831 anti-FAK phospho (Tyr576 Tyr577) antibody WB image
Western Blot: extracts from HT29 cells untreated or treated with PMA stained with anti-FAK (phospho Tyr576 Tyr577) antibody ARG51831.
ARG51136 anti-FAK antibody IHC-P image
Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-FAK antibody ARG51136 (left) or the same antibody preincubated with blocking peptide (right).
ARG51136 anti-FAK antibody ICC/IF image
Immunofluorescence: methanol-fixed HeLa cells stained with anti-FAK antibody ARG51136.
ARG51624 anti-FAK phospho (Tyr925) antibody ICC/IF image
Immunofluorescence: methanol-fixed HeLa cells stained with anti-FAK (phospho Tyr925) antibody ARG51624.
ARG51831 anti-FAK phospho (Tyr576 Tyr577) antibody ICC/IF image
Immunofluorescence: methanol-fixed HeLa cells stained with anti-FAK (phospho Tyr576 Tyr577) antibody ARG51831.
Probing the Expression of ASAP1 and FAK in nonsmall cell lung cancer and their clinicopathological significance
ARG51136: IHC-P / Human
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