Phospho p70 S6 Kinase Antibody Duo (Total, pS411)

Key features and details

  • 产品描述: p70S6 Kinase phosphorylates specifically ribosomal protein S6 in response to Insulin or several classes of mitogens. It has been shown to be required for cell growth, cell cycle progression and is involved in translational control mechanism. p70S6K can be phosphorylated by Ang II at the Ser-411 site and the phosphorylation appear to involve EGF receptor transactivation and inhibited by dominant-negative Ras. Dufner, A. and Thomas, G. (1999) Exp Cell Res 253, 100-9. Eguchi, S. (1999) JBC(274): 36843-51
  • 靶点名称: p70 S6 Kinase
  • 別名: Phospho p70 S6 Kinase antibody; p70 S6 Kinase antibody; p70 S6 Kinase phospho (Ser411) antibody
  • Brand:
CAT.NO. : ARG30202
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Product Details
内含物
货号内含物名称宿主克隆性反应应用包装
ARG51236anti-p70 S6 Kinase antibodyRabbit pAbHu, Ms, RatICC/IF, IHC-P, WB50 μl
ARG51753anti-p70 S6 Kinase phospho (Ser411) antibodyRabbit pAbHu, Ms, RatICC/IF, IHC-P, WB50 μl
概述
产品描述p70S6 Kinase phosphorylates specifically ribosomal protein S6 in response to Insulin or several classes of mitogens. It has been shown to be required for cell growth, cell cycle progression and is involved in translational control mechanism. p70S6K can be phosphorylated by Ang II at the Ser-411 site and the phosphorylation appear to involve EGF receptor transactivation and inhibited by dominant-negative Ras. Dufner, A. and Thomas, G. (1999) Exp Cell Res 253, 100-9. Eguchi, S. (1999) JBC(274): 36843-51
靶点名称p70 S6 Kinase
別名Phospho p70 S6 Kinase antibody; p70 S6 Kinase antibody; p70 S6 Kinase phospho (Ser411) antibody
属性
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
全名Antibody Duo for Phospho p70 S6 Kinase (Total, pS411)
研究领域Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody
检测图片 (6)
  • ARG51236 anti-p70 S6 Kinase antibody WB image

    Western blot: 30 µg of HeLa cell lysate stained with ARG51236 anti-p70 S6 Kinase antibody at 1:500 dilution.

  • ARG51753 anti-p70 S6 Kinase phospho (Ser411) antibody WB image

    Western Blot: extracts from MCF cells untreated or treated with EGF stained with anti-p70 S6 Kinase (phospho Ser411) antibody ARG51753.

  • ARG51236 anti-p70 S6 Kinase antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-p70 S6 Kinase antibody ARG51236 (left) or the same antibody preincubated with blocking peptide (right).

  • ARG51236 anti-p70 S6 Kinase antibody ICC/IF image

    Immunofluorescence: methanol-fixed MCF7 cells stained with anti-p70 S6 Kinase antibody ARG51236.

  • ARG51753 anti-p70 S6 Kinase phospho (Ser411) antibody ICC/IF image

    Immunofluorescence: methanol-fixed MCF7 cells stained with anti-p70 S6 Kinase (phospho Ser411) antibody ARG51753.

  • ARG51753 anti-p70 S6 Kinase phospho (Ser411) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-p70 S6 Kinase (phospho Ser411) antibody ARG51753 (left) or the same antibody preincubated with blocking peptide (right).

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