PMS2 Rabbit Monoclonal Antibody(ARM882)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6672
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Postmeiotic Segregation Increased 2 (PMS2) is a DNA repair protein involved in mismatch repair. Mutations and deficiencies in the PMS2 gene have been linked to microsatellite instability and malignancies such as hereditary nonpolyposis colorectal cancer and endometrial cancer. Expression levels of the PMS2 protein may be useful as a screening tool for Lynch syndrome after a colorectal cancer diagnosis. Anti-PMS2 is recommended to be used as part of a panel along with antibodies against MSH2, MSH6, and MLH1.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Host Species |
rabbit monoclonal antibody |
|
Molecular Weight |
96 kDa |
|
Purity |
ProA affinity purified IgG |
|
Species Cross-reactivity |
Human |
|
Form |
Liquid |
|
Immunogen |
Synthetic peptide corresponding to residues within aa1-100 of PMS2 |
Data
Immunohistochemical staining of human colon cancer tissue using PMS2 Rabbit Monoclonal Antibody (ARM882).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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