Postsynaptic Receptor Antibody Panel (NMDAR2A, NMDAR2B, GluR1)
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Product Details
| 货号 | 内含物名称 | 宿主克隆性 | 反应 | 应用 | 包装 |
|---|---|---|---|---|---|
| ARG52358 | anti-NMDAR2A antibody | Rabbit pAb | Ms, Rat, Rb | IHC-Fr, WB | 50 μl |
| ARG52363 | anti-NMDAR2B antibody | Rabbit pAb | Ms, Rat | WB | 50 μl |
| ARG52314 | anti-GluR1 antibody [RH95] | Mouse mAb | Ms, Rat | WB | 50 μl |
| ARG65350 | Goat anti-Mouse IgG antibody (HRP) | Goat pAb | Ms | ELISA, IHC-P, WB | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
| 产品描述 | Synaptic plasticity, the variable efficacy of neurotransmission at synapses, is thought to form the memories. Glutaminergic synapses mediate virtually all excitatory neurotransmission in mammalian brains. Glutamate released from presynaptic terminals activates several types of glutamate-gated ion channels on postsynaptic membranes, including a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, consist of subunits GluR1-GluR4, and N-methyl-D-aspartate (NMDA) receptors. Changes in AMPA receptors at the postsynaptic membrane cause changes in synaptic strength, the best-characterized forms of which are long-term potentiation (LTP) and long-term depression (LTD). This antibody panel could be used to investigate the ratio of NMDAR to AMPAR or the change of AMPAR on the postsynaptic membrane. During the LTP, the AMPARs increase expression on the membrane of post-synapse, and the ratio of NMDAR to AMPAR would be higher than the pre-LTP. In construct, LTD decreases the AMPARs expression, and the ratio would be lower than pre-LTD. |
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| 靶点名称 | Postsynaptic Receptor |
| 別名 | Postsynaptic Receptor antibody; GluR1 antibody; NMDAR2A antibody; NMDAR2B antibody |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
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| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 全名 | Antibody Panel for Postsynaptic Receptor (NMDAR2A, NMDAR2B, GluR1) |
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| 研究领域 | Immune System antibody; Neuroscience antibody |
ARG52358 anti-NMDAR2A antibody WB image
Western Blot: 10 µg of Rat hippocampal (Hipp) lysate stained with ARG52358 anti-NMDAR2A antibody showing specific immunolabeling of the ~180 kDa NR2A subunit of the NMDA receptor.
ARG52314 anti-GluR1 antibody [RH95] WB image
Western Blot: rat hippocampal lysate showing specific immunolabeling of the ~105k GluR1 protein stained with GluR1 antibody (ARG52314).
ARG52363 anti-NMDAR2B antibody WB image
Western blot: 10 ug of rat hippocampal (Hipp) lysate stained with ARG52363 anti-NMDAR2B antibody showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.
ARG52358 anti-NMDAR2A antibody IHC-Fr image
Immunohistochemistry: Rabbit retina stained with ARG52358 anti-NMDAR2A antibody showing NR2A in the rod and cone photoreceptors in the outer plexiform layer as well as the entire inner plexiform layer.
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ARG65350: WB /
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