PRDM1 Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human, Mouse, Rat
- Application:WB, IHC-P, FC
- Host:Rabbit
- Clonality:Polyclonal
- lsotype:IgG
- Target:PRDM1
-
Brand:
CAT.NO. : ARA6810
RMB Please choose
RMB Please choose
Product Details
Background
Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (By similarity). Binds specifically to the PRDI element in the promoter of the beta-interferon gene . Drives the maturation of B-lymphocytes into Ig secreting cells . Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (By similarity).
Application
|
Application |
Dilution Ratio |
|
WB |
1:500 - 1:1000 |
|
FC |
1:50 - 1:100 |
|
IHC-P |
1:100 - 1:500 |
Overview
|
Product Name |
PRDM1 Rabbit Polyclonal Antibody |
|
Antibody Type |
Rabbit Polyclonal Antibody |
|
Immunogen |
Synthetic peptide within Human aa 770-825 / 825 |
|
Species Reactivity |
Human, Mouse, Rat |
|
Validated Applications |
IHC-P, FC, WB |
|
Molecular Weight |
Predicted band size: 92 kDa |
|
Positive Control |
Rat cervix tissue, human skin tissue, human esophagus tissue, mouse esophagus tissue, PANC-1, mouse kidney tissue lysate, rat kidney tissue lysate |
|
Conjugation |
unconjugated |
|
Form |
Liquid |
|
Storage Buffer |
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG |
|
Purification Method |
Immunogen affinity purified |
Data
Western blot analysis of PRDM1 on different lysates with PRDM1 antibody
Immunohistochemical analysis of paraffin-embedded rat cervix tissue using anti-PRDM1 antibody.
Flow cytometric analysis of PRDM1 was done on PANC-1 cells.
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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