Prohibitin Mouse Monoclonal Antibody(ARA728)
Key features and details
- Reactivity:Human, Rat, Pig, Mouse
- Application:WB, IHC, ELISA, IF, IP
- Host:Mouse
- Clonality:Monoclonal
- Target:Prohibitin
-
Brand:
CAT.NO. : ARA6515
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Product Details
Background
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500 - 1:2000 |
|
IHC |
1:50 - 1:500 |
Overview
|
Validated Applications |
WB, IHC, ELISA, IF, IP |
|
Species Reactivity |
Human, Rat, Pig, Mouse |
|
Immunogen |
Recombinant human Prohibitin protein |
|
Host/Isotype |
Mouse / IgG1 |
|
Full Name |
prohibitin |
|
Alternative Names |
PHB, 4D3G5, PHB1, Prohibitin 1 |
|
Molecular Weight |
30 kDa |
|
GenBank Protein Accession |
BC013401 |
|
Gene Name |
Prohibitin |
|
Gene ID (NCBI) |
5245 |
|
Conjugation Type |
Unconjugated |
|
Form |
Liquid |
|
Purification Method |
Protein G purification |
|
UNIPROT ID |
P35232 |
|
Storage Buffer |
PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
Data
Various lysates were subjected to SDS PAGE followed by western blot with Prohibitin Mouse Monoclonal Antibody(ARA728).
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using Prohibitin Mouse Monoclonal Antibody(ARA728).
Immunofluorescent analysis of Hela cells, using Prohibitin Mouse Monoclonal Antibody(ARA728).
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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