pTau205 Mouse Monoclonal Antibody(ARA990)
Key features and details
- Reactivity:Human
- Application:Sandwich ELISA
- Host:Mouse
- Clonality:Monoclonal
- Target:pTau205
-
Brand:
CAT.NO. : ARA6888
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Product Details
Background
pTau205 (phosphorylated tau at position 205) is a developing biomarker for Alzheimer's disease (AD) specifically linked to the presence and advancement of mature tau neurofibrillary tangles (NFTs), a key feature of the disease.
Application
| Recommended dilution ratio | |
|---|---|
| Sandwich ELISA | 1:100-1:200 |
Formulation
| ARA6888 | Phosphate-buffered saline (PBS), carrier-free, with optional 0.09% sodium azide |
|---|---|
| ARA6888-T5/20/50/100 | Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
Overview
|
Antibody specificity |
Raised against a peptide immunogen containing phosphorylated T205. The antibody recognizes the pTau protein with an epitope containing phosphorylated T205. The antibody also weakly reacts with phosphoryla |
|
Species reactivity |
Human |
|
Clonality |
Monoclonal |
|
Host / isotype |
Mouse / IgG1 |
|
Immunogen |
Human MAPT peptide |
|
Cross reactivity |
Not tested |
|
Recombinant |
Not recombinant |
|
Purification |
Protein A purification |
|
Form |
Liquid |
|
Conjugation |
Unconjugated |
Data
Sandwich ELISA analysis of pTau205 by ARA6887 & ARA6837.
Microtiter plates were coated with ARA6887 as the capture antibody. Recommbinant pTau205 protein was applied as the antigen. Biotin-conjugated Tau (S305) Mouse Monoclonal Antibody(ARA971) served as the detection antibody, followed by streptavidin-HRP incubation.
Result: ARA6887 and ARA6837 can be used as a matched antibody pair to detect and quantify the concentration of pTau205.
Storage
Shipped at ambient temperature or with ice packs. Avoid repeated freeze-thaw cycles.
Upon receipt,
* 1 month when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Upon receipt,
* 1 month when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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