PXA-5(BSAP) Mouse Monoclonal Antibody(ARM901)

Key features and details

Target: PXA-5(BSAP)
Clone ID: ARM901
Host Species: Mouse
Species Cross-reactivity: Human
Applications: IHC-P
Dilution: 1:100-1:200
Clonality: Monoclonal

Brand:

CAT.NO. : ARM6691

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Size:

1mL

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Product Details

Background

PAX-5 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. The PAX-5 gene encodes the B-cell lineage specific activator protein (BSAP), whose expression is limited to early stages of B-cell differentiation. Anti-PAX-5 is useful in differentiating between classic Hodgkin's lymphoma versus multiple myeloma and solitary plasmacytoma, as the protein is expressed in mature and precursor B-cell non-Hodgkin's lymphomas/leukemias while being absent from the other two conditions. Diffuse large B-cell lymphomas are positive for PAX-5, with the exception of those with terminal B-cell differentiation, and T-cell neoplasms do not stain with Anti-PAX-5.

Application

Application	Dilution Ratio
IHC	1:100- 1:200

Overview

Molecular Weight	38,890 Da
3D Structure	ModBase 3D Structure for Q02548
Host	Mouse
Species Reactivity	Human
Form/Format	Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Positive Control	Tonsil