Pyrimidine Dimer ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
- 标准范围:
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Brand:
CAT.NO. : ARG83380
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Product Details
概述
| 产品描述 | ARG83380 Pyrimidine Dimers ELISA Kit is an Enzyme Immunoassay kit for the quantification of Pyrimidine Dimer in Cell / Tissue genomic DNA |
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| 反应物种 | Other |
| 应用 | ELISA |
| 靶点名称 | Pyrimidine Dimer |
| 偶联标记 | HRP |
| 偶联标记说明 | Read at 450 nm. |
| 灵敏度 | 0.8 ng/mL |
| 样品类型 | Cell / Tissue genomic DNA |
| 标准范围 | 1.56 - 100 ng/mL |
| 样本量 | 50 µL |
应用说明
| 检测时间 | ~3.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store components at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | Absorption of ultraviolet (UV) light produces two predominant types of DNA damage, cyclobutane pyrimidine dimers and pyrimidine pyrimidone photoproducts. The result is a transition of C to T and CC to TT, which are the most frequent mutations of p53 in both human and mouse skin cancers. UV damaged DNA is usually repaired by nucleotide excision repair or base excision repair. After UV exposure, cells activate p53 and stall the cell cycle for repair. If the damage is too severe, the cell will trigger apoptosis to get rid of DNA damaged, potentially mutant cells. |
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| 研究领域 | DNA, MutationDimers (chemistry), DNA replication and repair-deficiency disorders, Senescence, Cyclobutanes |
检测图片 (1)
ARG83380 Pyrimidine Dimer ELISA Kit standard curve image
ARG83380 Pyrimidine Dimer ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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