Rat Antithrombin III ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
- 标准范围:
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Brand:
CAT.NO. : ARG83482
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Product Details
概述
| 产品描述 | ARG83482 Rat Antithrombin III ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat Antithrombin III in Plasma, Serum and Urine |
|---|---|
| 反应物种 | Rat |
| 应用 | ELISA |
| 靶点名称 | Antithrombin III |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 6.25 ng/ml |
| 样品类型 | Plasma, Serum and Urine |
| 标准范围 | 12.5 - 400 ng/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | SERPINC1; Serpin Family C Member 1; ATIII; AT3; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; Serpin Peptidase Inhibitor, Clade C (Antithrombin), Member 1; Antithrombin-III; MGC22579; Coding Sequence Signal Peptide Antithrombin Part 1; Serpin Peptidase Inhibitor Clade C Member 1; Signal Peptide Antithrombin Part 1; Antithrombin (Aa 375-432); Antithrombin III; Serpin C1; ATIII-R2; ATIII-T1; ATIII-T2; THPH7; AT3D |
应用说明
| 检测时间 | 2 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | SERPINC1 |
|---|---|
| 全名 | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
| 背景介绍 | The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. A reduction in the serum level of this protein is associated with severe cases of Coronavirus Disease 19 (COVID-19). |
| 生物功能 | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
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