Rat IL18 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- Protein Full name:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG83008
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Product Details
概述
| 产品描述 | ARG83008 Rat IL18 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat IL18 in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
|---|---|
| 反应物种 | Rat |
| 应用 | ELISA |
| 靶点名称 | IL18 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| Protein Full name | Interleukin-18 |
| 灵敏度 | 15.6 pg/ml |
| 样品类型 | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
| 标准范围 | 31.25 - 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | IL18, Interleukin 18, IL1F4, IL 18, IGIF, IL 1g, Interleukin 18 (Interferon-Gamma-Inducing Factor), IFN Gamma Inducing Factor, Interleukin 1 Gamma, Interleukin 18, Iboctadekin, IL 1 Gamma, Interferon Gamma Inducing Factor, Interferon Gamma Inducing Factor |
应用说明
| 检测时间 | ~ 4 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL18 |
| 全名 | Interleukin 18 |
| 背景介绍 | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] |
| 生物功能 | Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. [UniProt] |
| 细胞定位 | Cytoplasm, Secreted. [UniProt] |
| 产品亮点 | Related products: IL18 antibodies; IL18 ELISA Kits; IL18 recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | The pro-IL-18 precursor is processed by CASP1 or CASP4 to yield the active form. [UniProt] |
检测图片 (1)
ARG83008 Rat IL18 ELISA Kit standard curve image
ARG83008Rat IL18 ELISA Kit results of standard run with optical density reading at 450 nm
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