Rat PLXNA3 / Plexin-A3 ELISA Kit
Key features and details
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- 反应物种:
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- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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CAT.NO. : ARG83465
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Product Details
概述
| 产品描述 | ARG83465 Rat PLXNA3 / Plexin-A3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat PLXNA3 / Plexin-A3 in Serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Rat |
| 应用 | ELISA |
| 靶点名称 | PLXNA3 / Plexin-A3 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 15 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 31.2 - 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | PLXNA3; Plexin A3; XAP-6; Plxn3; PLXN4; SEX; 6.3; Semaphorin Receptor SEX; Plexin-A3; Plexin-4; Sex Chromosome X Transmembrane Protein Of HGF Receptor Family 3; HSSEXGENE |
应用说明
| 检测时间 | 3.5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PLXNA3 |
| 全名 | Plexin A3 |
| 背景介绍 | This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013] |
| 生物功能 | Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
| 细胞定位 | Cell membrane, Membrane |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
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