Recombinant Human Interferon-gamma

Key features and details

  • Species: Human
  • Abbreviation: rHuIFN-γ
  • Source: Expressed in E. coli.
  • Molecular Weight: Approximately 16.9 kDa, a single non-glycosylated polypeptide chain containing 144 amino acids.
  • Purity: >98% by SDS-PAGE or HPLC.
  • Endotoxin: < 0.01 EU/μg of rHuIFN-γ protein as determined by LAL method.
  • Accession #: P01579 Gln2-Gln166 with an N-terminal Met
  • Storage: -20.0°C
  • Brand:
CAT.NO. : ARP6612
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Product Details
Background
Interferon-gamma (IFN-γ) , also known as Type II interferon or immune interferon, is a dimerized soluble cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. It is produced primarily by CD4 and CD8 T lymphocytes as well as natural killer (NK) and natural killer T (NKT) cells. The primary role for IFN-γ is the activation of macrophages to increase phagocytosis, tumoricidal properties, and intracellular killing of pathogens. IFN-γ also increases expression of MHC antigens by macrophages and this facilitates antigen presentation to T cells. The recombinant Interferon-gamma s a 16.9kDa protein consisting of 144 amino acid.
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