Recombinant Human Interleukin-16
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CAT.NO. : ARP6646
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Product Details
Background
IL-16 (also called lymphocyte chemoattractant factor) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. it has three isoforms which are cleaved from pre-Interleukin-16. It has many functions including induction of the IL-2Rα on T cells, suppression of human immunodeficiency virus (HIV) replication, inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on. Furthermore, recombinant human IL-16 (130a.a.) shares 85%a.a. sequence identity with murine IL-16, Human and murine IL-16 shows significant cross-species reactivity. Recombinant Human IL-16 is a 13.4kDa globular protein containing 130 amino acid.
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