Recombinant Human Interleukin-19
Key features and details
- Species:
- Abbreviation:
- Source:
- Molecular Weight:
- Purity:
- Endotoxin:
- Accession #:
- Storage:
-
Brand:
CAT.NO. : ARP6647
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
Background
Human Interleukin-19 (IL-19) is encoded by the IL19 gene, which is located on the chromosome 1. The protein belongs to the IL-10 family that includes IL-10, IL-20, IL-22, IL-24, and IL-26. As a monomer made of seven amphipathic helices, IL-19 has a helical bundle and shares the same cell surface receptor (IL-20R) with IL-20 and IL-24. It may play some important roles in inflammatory responses because it up-regulates IL-6 and TNF-alpha and induces apoptosis through TNF-α. Human and murine IL-19 share 71% amino acid sequence identity. Although mouse IL-19 is active on human cells, human IL-19 is not active on mouse cells. In solution, IL-19 exists predominantly as a non-disulfide-linked dimer. Recombinant Human IL-19 is a 17.9kDa globular protein containing 153 amino acid.
New Products
