Recombinant Human Keratinocyte Growth Factor/ Fibroblast Growth Factor 7
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CAT.NO. : ARP6779
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Product Details
Background
KGF (also known as FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF/FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF-7 signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, as well as in angiogenesis and wound healing. KGF actives on keratinocytes, and exhibits mitogenic activity for epidermal cells, but essentially no activity for fibroblasts. KGF has species cross active, human KGF shares 96% and 92% amino acid sequence identity with murine and rat FGF-7, respectively. Recombinant Human KGF/FGF-7 is an 18.9kDa protein consisting of 163 amino acid.
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