Recombinant Human Prolactin

Key features and details

  • Species: Human
  • Abbreviation: rHuProlactin
  • Source: Expressed in E. coli.
  • Molecular Weight: Approximately 23.0 kDa, a single non-glycosylated polypeptide chain containing 200 amino acids.
  • Purity: >98% by SDS-PAGE or HPLC.
  • Endotoxin: < 0.01 EU/μg of rHuProlactin protein as determined by LAL method.
  • Accession #: P01236 Leu29-Cys227 with an N-terminal Met
  • Storage:
  • Brand:
CAT.NO. : ARP6664
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Product Details
Background
Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoregulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Human prolactin shares only 60% and 63% amino acid sequence identity with mouse and rat prolactin, respectively, although rat prolactin can activate the human prolactin receptor. Recombinant Human Prolactin is a 23.0kDa globular protein containing 200 amino acid residues.
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