Recombinant Human Prolactin
CAT.NO. : ARP6664
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Background
Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoregulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Human prolactin shares only 60% and 63% amino acid sequence identity with mouse and rat prolactin, respectively, although rat prolactin can activate the human prolactin receptor. Recombinant Human Prolactin is a 23.0kDa globular protein containing 200 amino acid residues.
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