Recombinant Human Signal Recognition Particle Subunit SRP54

Key features and details

  • Species: Human
  • Abbreviation: rHuSRP54
  • Source: Expressed in E. coli.
  • Molecular Weight: Approximately 56.84 kDa, a single non-glycosylated polypeptide chain containing 515 amino acids.
  • Purity: >96% by SDS-PAGE or HPLC.
  • Endotoxin:
  • Accession #: P61011 Met1-Met504 with a C-terminal flag tag
  • Storage:
  • Brand:
CAT.NO. : ARP6783
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Product Details
Background
SRP54, as part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. SRP54 is component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the co-translational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) , It Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein) . Recombinant Human SRP54 is a 56.84kDa protein globular protein containing  515 amino acid.
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