Recombinant Human Tau (acetyl K274) Protein
Key features and details
- Product Name:
- Expression Systems:
- Species:
- Formulation:
-
Brand:
CAT.NO. : AXP6624
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Size:
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Product Details
Background
Tau (acetyl K274) refers to the tau protein with an acetyl group attached at the lysine 274 residue, a modification strongly linked to Alzheimer's disease (AD), promoting synaptic dysfunction, memory loss, and increased aggregation by disrupting protein interactions, especially with the memory protein KIBRA, and altering mitochondrial dynamics, making it a key pathological feature of tauopathies.
Overview
|
Protein name |
Microtubule-associated protein tau |
|
Gene name |
MAPT |
|
Organism |
Homo sapiens (Human) |
|
Product name |
Recombinant Human Tau(acetyl K274) Protein |
|
Predicted molecular mass |
48 kDa |
|
Expression host |
Escherichia coli |
|
Modification |
Acetylation |
|
Purification tag |
6xHis at C-terminus |
|
Usage |
This product is validated for use as an immunogen and as a reagent in immunological assays |
|
Form |
Liquid |
|
Buffer |
Phosphate buffered saline |
Storage
Shipped on dry ice. Avoid repeated freeze-thaw cycles.
Upon receipt,
* 2 days when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Upon receipt,
* 2 days when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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