Recombinant Human Tau Protein
Key features and details
- Product Name:
- Expression Systems:
- Species:
- Formulation:
-
Brand:
CAT.NO. : AXP6617
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Size:
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Product Details
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Overview
|
Protein name |
microtubule associated protein tau |
|
Gene name |
MAPT |
|
Accession |
P10636-8 |
|
Organism |
Homo sapiens (Human) |
|
Product name |
Recombinant Human Tau Protein |
|
Predicted molecular mass |
47 kDa |
|
Expression host |
Escherichia coli |
|
Purification tag |
6xHis at C-terminus |
|
Usage |
This product is validated for use as an immunogen and as a reagent in immunological assays |
|
Form |
Liquid |
|
Buffer |
Phosphate buffered saline |
Data
Left: The purified protein was run on 15% SDS-PAGE at reducing conditions. The gel was then stained with Coomassie brilliant blue and destained. Right: Western Blotting using HRP conjugated 6xHis antibody. Note: The molecular weight of the protein as observed on SDS-PAGE under reducing conditions may differ from its predicted value, due to variations in electrophoretic mobilities.
Storage
Shipped on dry ice. Avoid repeated freeze-thaw cycles.
Upon receipt,
* 2 days when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Shipped at ambient temperature or with ice packs.
Upon receipt,
* Lyophilized form: 12 months when stored at -20 °C or below, protected from light and moisture.
* After reconstitution: aliquot to avoid repeated freeze-thaw cycles:
• 2 days when stored at 2 to 8 °C.
• 3 months when stored at -20 °C or below.
Upon receipt,
* 2 days when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Shipped at ambient temperature or with ice packs.
Upon receipt,
* Lyophilized form: 12 months when stored at -20 °C or below, protected from light and moisture.
* After reconstitution: aliquot to avoid repeated freeze-thaw cycles:
• 2 days when stored at 2 to 8 °C.
• 3 months when stored at -20 °C or below.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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