Recombinant Human TNF Ligand-related Molecule 1/TNFSF15
Key features and details
- Species:
- Abbreviation:
- Source:
- Molecular Weight:
- Purity:
- Endotoxin:
- Accession #:
- Storage:
-
Brand:
CAT.NO. : ARP6685
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
Background
TL-1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15) . TL-1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-α and IL-1α. TL-1A binds with high affinity to death receptor 3 (DR3) , known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL-1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis. Recombinant Human TL-1A/TNFSF15 is a 20.5kDa globular protein containing 180 amino acid residues.
New Products
