Recombinant Murine Heparin-binding EGF-like Growth Factor
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CAT.NO. : ARP6732
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Background
Heparin-binding epidermal growth factor (HB-EGF) -like growth factor (EGF) is found in cerebral neurons. Its expression is increased after hypoxic or ischemic injury, which also stimulates neurogenesis. HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation, wound healing, and in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HB-EGF is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues. Mouse HB-EGF shares about 73% a.a. sequence identity with human HB-EGF. Recombinant murine HB-EGF is a 9.8kDa protein containing 86 amino acid residues.
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