Recombinant Murine Interleukin-7
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CAT.NO. : ARP6694
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Product Details
Background
Interleukin-7 (IL-7) is encoded by the IL7 gene in mouse and secreted by stromal cells in the red marrow and thymus. The protein signals through the IL-7 receptor, which is a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and it can stimulate proliferation of B cells, T cells and NK cells. Murine IL-7 has approximately 65% and 88% amino acid sequence identity with human and rat IL-7 respectively and both proteins exhibit cross-species activity. Recombinant Murine IL-7 is a 14.9kDa globular protein containing 129 amino acid.
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