Recombinant Murine Keratinocyte Growth Factor-2/FGF10

Key features and details

  • Species: Murine
  • Abbreviation: rMuKGF-2/FGF10
  • Source: Expressed in E. coli.
  • Molecular Weight: Approximately 19.5 kDa, a single non-glycosylated polypeptide chain containing 173 amino acids.
  • Purity: >96% by SDS-PAGE or HPLC.
  • Endotoxin: < 0.1 EU/μg of rMuKGF-2/FGF10 protein as determined by LAL method.
  • Accession #: O35565 Gln37-Thr209
  • Storage:
  • Brand:
CAT.NO. : ARP6737
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Product Details
Background
Fibroblast growth factor 10, also known as Keratinocyte Growth Factor-2 belongs to the fibroblast growth factor (FGF) family which is involved in a variety of biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Like most other FGF family members, FGF-10 is a heparin-binding growth factor that belongs to the FGF family.  Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Murine FGF-10 shares 94% and 100% a.a. sequence identity with human and rat FGF-10 respectively. Recombinant Murine FGF-10 is a 19.5kDa protein consisting of 173 amino acid.
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