Recombinant Murine Stem Cell Factor

Key features and details

  • Species: Murine
  • Abbreviation: rMuSCF
  • Source: Expressed in E. coli.
  • Molecular Weight: Approximately 18.4 kDa, a single non-glycosylated polypeptide chain containing 165 amino acids.
  • Purity: >97% by SDS-PAGE or HPLC.
  • Endotoxin: < 0.1 EU/μg of rMuSCF protein as determined by LAL method.
  • Accession #: P20826 Lys26-Ala190
  • Storage: -20.0°C
  • Brand:
CAT.NO. : ARP6629
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Product Details
Background
Stem Cell Factor (SCF) which binds to the c-Kit receptor is produced by fibroblasts and endothelial cells. The soluble and transmembrane forms of the protein are formed by alternative splicing of the same RNA transcript and the presence of both soluble and transmembrane It is required for normal hematopoietic function and plays an important role in hematopoiesis, spermatogenesis, and melanogenesis. It also promotes mast cell adhesion, migration, proliferation, and survival. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant murine SCF is an 18.4kDa polypeptide containing  165 amino acid.
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