Reverse T3 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG83086
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Product Details
概述
| 产品描述 | ARG83086 Reverse T3 ELISA Kit is an enzyme immunoassay kit for the quantitative of Human Reverse T3 in Serum. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Not reacts withT3, T4 and T2. |
| 靶点名称 | Reverse T3 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 14 pg/ml |
| 样品类型 | Serum and plasma |
| 标准范围 | 20 – 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 5.0% Inter-Assay CV: less than 8.5% |
| 別名 | Reverse triiodothyronine |
应用说明
| 检测时间 | ~2.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | Reverse T3 (rT3) is a metabolically inactive form of thyroid hormone, which is generated from T4 via the type 3 5′-deiodinase enzyme. In addition to producing rT3, the type 3 5′-deiodinase enzyme is also responsible for decomposing rT3 into inactive diiodothyronine. In nonthyroidal illness states, rT3 levels are elevated because of (1) increased production of rT3 from T4 and (2) reduced clearance of rT3 to diiodothyronine. In hypothyroidism, rT3 levels are typically low due to reduced production of the precursor (i.e., T4), although in mild hypothyroidism rT3 levels may sometimes be normal or high. In contrast, rT3 levels typically remain normal in kidney dysfunction. |
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