SALL4 Rabbit Monoclonal Antibody(ARB543)
CAT.NO. : ARB6835
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Background
Sal-like protein 4 (SALL4) serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities. Members of the SALL gene family encode putative zinc finger transcription factors highly expressed during development.
SALL4 is expressed very early in development with other pluripotency regulators, such as Oct-4 and Nanog. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas. SALL4 expression is also seen in the spermatogonia of normal testis.
SALL4 is expressed very early in development with other pluripotency regulators, such as Oct-4 and Nanog. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas. SALL4 expression is also seen in the spermatogonia of normal testis.
Application
Application |
Dilution Ratio |
IHC |
1:100 - 1:200 |
Overview
Predicted Molecular Wt |
112kDa |
Species Cross-reactivity |
Human |
Applications |
IHC-P |
Purity |
ProA affinity purified IgG |
Form |
Liquid |
Swissprot ID |
Q9UJQ4 |
Subcellular location |
Nucleus |
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data

Immunohistochemical staining of human seminoma tissue using SALL4 Rabbit Monoclonal Antibody(ARB543)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
