SATB2 Rabbit Monoclonal Antibody(ARM643)

Key features and details

  • Target: SATB2
  • Clone ID: ARM643
  • Host: Rabbit
  • Species Cross-reactivity: Human
  • Applications: IHC
  • Dilution: 1:50-1:200
  • Clonality: Monoclonal
  • Brand:
CAT.NO. : ARM6934
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Product Details
Background
Special AT-Rich Sequence-Binding Protein 2 (SATB2), also known as DNA-binding protein SATB2, is a protein involved in transcriptional regulation and chromatin remodeling. It has been identified as a potentially useful marker for neuroendocrine neoplasms or carcinomas of the colon and rectum, as well as for detecting osteoblastic differentiation in benign and malignant mesenchymal tumours. When used in combination with Cytokeratin 20 and Cadherin-17, SATB2 is able to help identify the large majority of colorectal carcinomas. Anti-SATB2 is useful for identifying colorectal carcinomas when working on a tumour of unknown origin, since upper gastrointestinal carcinomas, pancreatic ductal carcinomas, ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origins are all typically negative for SATB2.
Application

Application

Dilution Ratio

IHC

1:50 - 1:200

Overview

Molecular Weight

69,137 Da

3D Structure

ModBase 3D Structure for Q9UPW6

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Purified

Form/Format

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Immunogen

Recombinant Protein

Data

Immunohistochemical staining of human colon adenocarcinoma tissue using SATB2 Rabbit Monoclonal Antibody (ARM643).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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