SATB2 Rabbit Monoclonal Antibody(ARM643)
CAT.NO. : ARM6934
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Background
Special AT-Rich Sequence-Binding Protein 2 (SATB2), also known as DNA-binding protein SATB2, is a protein involved in transcriptional regulation and chromatin remodeling. It has been identified as a potentially useful marker for neuroendocrine neoplasms or carcinomas of the colon and rectum, as well as for detecting osteoblastic differentiation in benign and malignant mesenchymal tumours. When used in combination with Cytokeratin 20 and Cadherin-17, SATB2 is able to help identify the large majority of colorectal carcinomas. Anti-SATB2 is useful for identifying colorectal carcinomas when working on a tumour of unknown origin, since upper gastrointestinal carcinomas, pancreatic ductal carcinomas, ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origins are all typically negative for SATB2.
Application
Application |
Dilution Ratio |
IHC |
1:50 - 1:200 |
Overview
Molecular Weight |
69,137 Da |
3D Structure |
ModBase 3D Structure for Q9UPW6 |
Isotype |
IgG |
Host |
Rabbit |
Species Reactivity |
Human |
Purity/Purification |
Purified |
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Immunogen |
Recombinant Protein |
Data

Immunohistochemical staining of human colon adenocarcinoma tissue using SATB2 Rabbit Monoclonal Antibody (ARM643).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
