SF-1 Rabbit Monoclonal Antibody(ARB546)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6838
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Size:
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Product Details
Background
SF-1 is a transcriptional activator that essential for sexual differentiation and formation of the primary steroidogenic tissues. It also activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
SF-1 is highly expressed in the adrenal cortex, ovary, testis, spleen.
SF-1 is generally used for diagnosis of sex cord-stromal tumors and differential diagnosis of adrenocortical adenoma and pheochromocytoma.
SF-1 is highly expressed in the adrenal cortex, ovary, testis, spleen.
SF-1 is generally used for diagnosis of sex cord-stromal tumors and differential diagnosis of adrenocortical adenoma and pheochromocytoma.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:200 |
Overview
|
Predicted Molecular Wt |
52kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
Q13285 |
|
Subcellular location |
Nucleus |
|
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
|
Immunogen |
Full length protein corresponding to Human SF-1 |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human adrenal cortical adenoma tissue using SF-1 Rabbit Monoclonal Antibody(ARB546)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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