Smoothelin Mouse Monoclonal Antibody(ARM564)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6854
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Smoothelin is a protein found explicitly in the cytoskeletal component of differentiated (contractile) smooth muscle cells, while being absent from myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle. Anti-Smoothelin is often used as an aid in staging bladder carcinoma, as overexpression of the smoothelin protein is characteristic of muscularis propria invasion, while negative or weak staining is indicative of muscularis mucosae and the non-invasive form of the cancer. Anti-Smoothelin is also useful in differentiating benign smooth muscle tumours from malignant smooth muscle tumours.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:25 - 1:100 |
Overview
|
Molecular Weight |
101,810 Da |
|
3D Structure |
ModBase 3D Structure for P53814 |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human smooth muscle tissue using Smoothelin Mouse Monoclonal Antibody (ARM564).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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