SOX-10 Mouse Monoclonal Antibody(ARM565)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6855
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
SRY (Sex Determining Region Y)-Box 10 (SOX-10), also known as Transcription Factor SOX-10, is a nuclear transcription factor that acts in regulation of embryonic development and in the specification and differentiation of cells of melanocytic lineage. SOX-10 is diffusely expressed in neurofibromas and schwannomas, and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung's disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Clonality |
Monoclonal |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Form/Format |
Tris Buffer, pH7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
Data
Immunohistochemical staining of human melanoma tissue using SOX-10 Mouse Monoclonal Antibody (ARM565).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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