SOX10 Rabbit Monoclonal Antibody(ARB827)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6617
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Size:
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Product Details
Background
SOX10 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. During development, SOX10 first appears in the forming neural crest and continues to be expressed in Schwann cells. It is important for differentiation, maturation and maintenance of Schwann cells and melanocytes.
Overview
| Target | SOX10 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 50 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P56693 |
| Immunogen | Synthetic peptide corresponding to SOX10 residues within aa366-466 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Nucleus |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18° C-25°C) for 30 minutes |
Data
Immunohistochemical staining of human mammary carcinoma tissue sections was performed using SOX10 Rabbit Monoclonal Antibody (ARB827).
Immunohistochemical staining of human melanoma tissue sections was performed using SOX10 Rabbit Monoclonal Antibody (ARB827).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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