Thymidylate Synthase Rabbit Monoclonal Antibody(1182)
Datasheet
Key features and details
- Reactivity:Human
- ApplicationIHC(P)
- Host:Rabbit
- Clonality: Monoclonal
- Target:Thymidylate synthase; TS; TSase;
-
Brand:
CAT.NO. : ARA1182
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Size:
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Product Details
Background
Thymidylate synthase (TS) is an enzyme crucial for DNA synthesis, converting deoxyuridine monophosphate (dUMP) into deoxythymidine monophosphate (dTMP). This process is vital for forming the thymine base, a key component of DNA. TS is a target for certain cancer chemotherapy drugs, as inhibiting its activity can disrupt DNA replication and lead to cell death.
Overview
|
免疫原 |
Recombinant fusion protein of human Thymidylate Synthase. The exact sequence is proprietary. |
|
纯化方式 |
The antibody was purified by immunogen affinity chromatography. |
|
克隆类型 |
Monoclonal |
|
产品形式 |
Liquid in PBS, pH 7.3, 50% glycerol, and 0.05% Proclin300. |
|
基因名称 |
TYMS |
|
相关名称 |
TS; Thymidylate synthase; TS; TSase |
|
基因编号(人) |
7298; |
|
蛋白编号(人) |
P04818; |
Application
IHC: 1:100 - 1:500
Data
Immunohistochemical analysis of Thymidylate Synthase staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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