TIA-1 Mouse Monoclonal Antibody(ARM578)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6868
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
T-cell-restricted Intracellular Antigen-1 (TIA1) is an RNA-binding protein involved in apoptosis, which is present in natural killer cells and cytotoxic T cells. Anti-TIA1 stains hairy cell leukemia, large granular lymphocyte (LGL) leukemia, and T-cell lymphoma. As overexpression of TIA1 is characteristic of LGL leukemia and decreased levels of TIA1 is indicative of T-cell lymphocytosis and other T-cell diseases, Anti-TIA1 may be useful in distinguishing between these conditions. TIA1 could also be a useful marker for identifying tumour-infiltrating lymphocytes and understanding the immune response to cancers.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:25 - 1:100 |
Overview
|
Molecular Weight |
41,801 Da |
|
3D Structure |
ModBase 3D Structure for P31483 |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human tonsil tissue using TIA-1 Mouse Monoclonal Antibody (ARM578).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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