TRPS1 Rabbit Monoclonal Antibody(ARB847)
Datasheet
Key features and details
- Reactivity:Human
- Application:IHC-P
- Host:Rabbit
- Clonality:Monoclonal
- Target:TRPS1
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Brand:
CAT.NO. : ARB6637
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Product Details
Background
TRPS1 is a transcription factor that was initially discovered as being mutated in Tricho-rhino-phalangeal syndrome, a craniofacial and skeletal malformation syndrome. TRPS1 recognizes GATA sequences and represses the activation potential of other GATA factors. In addition, TRPS1 binds to the NuRD complex via CHD4 and can repress other key transcription factors such as p63 and estrogen receptor.
Overview
| Target | TRPS1 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 141 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | Q9UHF7 |
| Immunogen | Recombinant protein of TRPS1 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Nucleus |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), RT for 30 min |
Application
| Application | Dilution Ratio |
|---|---|
| IHC-P | 1:100 - 1:200 |
Data
Immunohistochemical staining of human breast tumor tissue sections using TRPS1 Rabbit Monoclonal Antibody (ARB847).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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