Type I Cytokeratins Rabbit Monoclonal Antibody(ARB857)

Key features and details

  • Target: Type I Cytokeratins
  • Clone ID: ARB857
  • Host: Rabbit
  • Molecular Weight: 60/53/51/45/40 kDa
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human
  • Applications: IHC-P
  • Swissprot ID: Not available
  • Brand:
CAT.NO. : ARB6648
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Size:
1mL
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Product Details
Background
The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation.This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.
Overview
Target Type I Cytokeratins
Host Species rabbit monoclonal antibody
Molecular Weight 60/53/51/45/40 kDa
Purity ProA affinity purified IgG
Species Cross-reactivity Human
Form Liquid
Applications IHC-P
Swissprot ID Not available
Immunogen Synthetic peptide corresponding to Type I Cytokeratins residues within aa100-200 of Type I Cytokeratins
Storage Buffer PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%
Storage Conditions -25°C to -18°C
Dilutions IHC-P: 1:100-1:200
Subcellular Location Cytoplasm
Recommended Method Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes
Data

Immunohistochemical staining of human uterine tissue sections using Type I Cytokeratins Rabbit Monoclonal Antibody (ARB857).
Immunohistochemical staining of human cervical carcinoma tissue sections using Type I Cytokeratins Rabbit Monoclonal Antibody (ARB857).
Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Research Use Only

For Research Use Only. Not for use in diagnostic procedures.

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