Uroplakin 1a（UPK1A) Rabbit Monoclonal Antibody(ARB567)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6859
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Size:
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Product Details
Background
Uroplakin 1a (UPK1A) is one out of 5 known uroplakin protein particles that cooperatively form apical asymmetric unit membrane (AUM) plaques which play an important role in the stabilization and strengthening of epithelial cells that line the bladder.
UPK1A is expressed in a limited number of normal tissues. A weak to moderate UPK1A staining can occur in some cell layers (middle third) of the squamous epithelium.
The significant advantage of moderate to strong membrane UPK1A immunostaining in urothelial carcinoma indicates that positive UPK1A staining has high specificity in distinguishing urothelial carcinoma form other tumors.
UPK1A is expressed in a limited number of normal tissues. A weak to moderate UPK1A staining can occur in some cell layers (middle third) of the squamous epithelium.
The significant advantage of moderate to strong membrane UPK1A immunostaining in urothelial carcinoma indicates that positive UPK1A staining has high specificity in distinguishing urothelial carcinoma form other tumors.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:200 |
Overview
|
Predicted Molecular Wt |
29kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
O00322 |
|
Subcellular location |
Membrane |
|
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human urothelial carcinoma tissue using Uroplakin 1a (UPK1A) Rabbit Monoclonal Antibody(ARB567)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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