Uroplakin II Monoclonal Antibody(ARB600)
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Rabbit
- Clonality:Monoclonal
- Target:Uroplakin II
-
Brand:
CAT.NO. : ARB6894
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Size:
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Product Details
Background
Uroplakin II is one of the four main members (Ia, Ib, II, III) of the Uroplakin family, and it is a specific glycoprotein associated with urothelial differentiation. Uroplakin II is negatively expressed in most normal tissues and is mainly highly expressed in urothelial carcinoma, which makes Uroplakin II mainly used to distinguish urothelial carcinoma from other tumors. The expression of Uroplakin II is correlated with the degree of differentiation of urothelial carcinoma, with a higher proportion of expression in better-differentiated cases. Compared with Uroplakin III, the immunohistochemistry of Uroplakin II has higher sensitivity for urothelial carcinoma.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:100-1:200 |
Overview
|
Positive Control |
Urothelial carcinoma |
|
Tissue Type |
FFPE |
|
Usage |
RUO |
|
Clone Number |
BP6308 |
|
Subcellular Location |
Cytoplasm, Cell membrane |
|
Retrieval Method |
HIER |
Data
Immunohistochemical staining of urothelial carcinoma tissue using Uroplakin II Monoclonal Antibody(ARB600)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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