Villin Rabbit Monoclonal Antibody(ARB569)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6861
RMB Please choose
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Villin is a 93 kDa calcium - regulated, actin - binding protein that plays a role in regulating actin filament assembly. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. In normal human tissue, villin is expressed by a limited number of simple epithelia of the gastrointestinal and urogenital tract. In tumor tissue, it is always expressed in colorectal cancer, hepatocellular carcinoma, endometrium cancer, as well as cancers of ovary and lung. Villin is a useful aid for classification of primary and metastatic colorectal carcinomas.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:200 |
Overview
|
Predicted Molecular Wt |
93kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
P09327 |
|
Subcellular location |
Cytoplasm |
|
Recommended method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
|
Immunogen |
Synthetic peptide corresponding to Villin residues within aa600 - 700 of Villin was used as an immunogen |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human colon adenocarcinoma tissue using Villin Rabbit Monoclonal Antibody(ARB569)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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