BG8, Lewis Y Mouse Monoclonal Antibody (IHC517)

Key features and details

  • Reactivity:Human
  • Application:IHC
  • Host:Mouse
  • Clonality:Monoclonal
  • lsotype:IgG1
  • Target:BG8, LewisY
  • Brand:
CAT.NO. : ARA8517
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Size:
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Product Details
Background
BG8 Lewisy, also known as Lewisy Blood Antigen or simply BG8, is a blood group antigen that has been identified in many studies as a potential marker for differentiation between pulmonary adenocarcinoma (PACA) and epithelioid mesothelioma (EM). It has been reported that sensitivity of non-mesothelial antigens for adenocarcinoma is organ-dependent. When attempting to differentiate epithelioid mesothelioma from adenocarcinoma, BG8 Lewisy performed at a sensitivity of 98% in the breast cancer group, and 100% in the lung cancer group.
Application
Dilution: IHC:1:50-1:200
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human lung cancer tissue sections labeling BG8 with  IHC517.
Storage
Store at -20°C. Stable for one year from the date of shipment. 
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