Recombinant Human p-Tau181 Protein
Key features and details
- Product Name:
- Expression Systems:
- Species:
- Formulation:
-
Brand:
CAT.NO. : AXP6613
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Size:
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Product Details
Background
The protein expressed by the MAPT gene promotes microtubule assembly and stability and might be involved in establishing and maintaining neuronal polarity. Its C-terminus binds axonal microtubules, and the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between the two. Axonal polarity is predetermined by MAPT localization within the neuronal cell's domain defined by the centrosome. The short isoforms allow cytoskeleton plasticity, whereas the longer isoforms may preferentially play a role in its stabilization. This supplementary information is collated from multiple sources and compiled automatically.
Overview
|
Protein name |
Microtubule-associated protein tau |
|
Gene name |
MAPT |
|
Accession |
P10636-8 |
|
Organism |
Homo sapiens (Human) |
|
Product name |
Recombinant Human p-Tau181 Protein |
|
Predicted molecular mass |
48 kDa |
|
Expression host |
Escherichia coli |
|
Modification |
Phosphorylation |
|
Purification tag |
6xHis at C-terminus |
|
Usage |
This product is validated for use as an immunogen and as a reagent in immunological assays |
|
Form |
Liquid |
|
Buffer |
Phosphate buffered saline |
Storage
Shipped on dry ice.
Avoid repeated freeze-thaw cycles. Upon receipt,
* 2 days when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Avoid repeated freeze-thaw cycles. Upon receipt,
* 2 days when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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